yang liu tsinghua
In 2015, we isolated a pathogenic multidrug-resistant strain of M. odoratus from a urinary tract infection (UTI) pa...Nonalcoholic steatohepatitis (NASH) is featured by the presence of hepatic steatosis combined with inflammation and hepatocellular injury. A number of reports have shown that toll‑like receptor 9 (TLR9) and B‑cell activating factor (BAFF) may be associated with IgAN; however, sufficient evidence has not yet to be delivered....A new series of 29 diarylpyrimidine analogues featuring a cyclopropylamino group between the pyrimidine scaffold and the aryl wing have been synthesized. Current vaccines against influenza A virus provide immunity to viral isolates similar to vaccine strains.
2016. State Farm Insurance. By mean of experimental investigation, the relationship of flow resistance and flow rate is obtained, and then utilized to acquire an accurate computation model. Inflammation and pro-inflammatory cytokines are generally regarded as inducers for adipocyte apoptosis, but whether some innate defects affect their susceptibility to cell death has not been extensively studied. However, molecular mechanisms of cavin-1 in the modulation of lipolysis remain poorly understood.
The cli...Endoplasmic reticulum (ER) stress activates the adaptive unfolded protein response (UPR) and represents a critical mechanism CCPD 2.0 totally covered 63.6% (438/689) of Chr.
The role of miR-410-3p in RMS cell invasion, migration, proliferation and apoptosis, and its possible mechanism were investigated in the curr...MicroRNA-874 (miR-874) is downregulated and acts as a tumor suppressor gene in several human cancers. As natural vectors, mosquitoes are very permissive to and allow systemic and persistent arbovirus infection. He emphasizes on computational imaging combined with compressive sensing and machine learning techniques. Intriguingly, persistent viral propagation in mosquito tissues neither results in dramatic pathological sequelae...Obesity is associated with chronic low-level inflammation, especially in fat tissues, which contributes to insulin resistance and type 2 diabetes mellitus (T2DM). Postdoctoral Researcher at Tsinghua University. Non-anastomotic strictures (NAS) are common biliary complications after liver transplantation (LT). With the rapid development of liquid chromatography tandem mass spectrometry technique, numerous studies on liver physiology and pa...Influenza A viruses are a major threat to human health and inflict a significant public health challenge worldwide.
Teachers College of Columbia University. The stem region of HA, which has been shown to be conserved, is the primary targ...Rhabdomyosarcoma (RMS) is one of the most common types of soft tissue sarcoma in children; however, the pathogenesis of RMS is unclear. However, a direct link between human type 1 diabetes and virus infection remains elusive. Gut-derived endotoxin plays a crucial role in the pathogenesis of NASH. Here, we...Zika virus (ZIKV) remained obscure until the recent explosive outbreaks in French Polynesia (2013-2014) and South America (2015-2016). Thioester (TE)-containing proteins (TEPs), which show hi...Although the mammalian IRE1α-XBP1 branch of the cellular unfolded protein response has been implicated in glucose and lipid metabolism, the exact metabolic role of IRE1α signalling in vivo remains poorly understood. In order to determine...Mosquito-borne viral diseases are a major concern of global health and result in significant economic losses in many countries. The pentose phosphate pathway (PPP), a branch of glycolysis, is an important metabolic pathway for the survival and biosynthesis of cancer cells. Many patients with portal hypertension require surgical treatment each year, and Hassab's operation, or esophagogastric devascularization and splenectomy, is an elective procedure. The NHR series developed by Institute of Nuclear and New Energy Technology in Tsinghua University us...A design of alarm system which includes both annuciator tiles and VDU alarm displays is proposed of the digital control room in HTR-PM (high temperature reactor pebble-bed module). A systematic review of Pubmed, Cochrane Library, Embase, Web of Science, Ovid database, China National Knowledge I...This paper reports the synthesis and antiviral evaluation of a series of non-nucleoside reverse transcriptase inhibitors (NNRTIs) that combine the peculiar structural features of diarylpyrimidine derivatives (DAPYs) and benzophenone derivatives (BPs).
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